1H-Indole-3-carboxaldehyde, 5-ethoxy-

1H-Indole-3-carboxaldehyde, 5-ethoxy- - Names and Identifiers

Name	5-ETHOXY-1H-INDOLE-3-CARBALDEHYDE
Synonyms	AKOS JY2083524 5-ETHOXYINDOLE-3-ALDEHYDE 5-ETHOXYINDOLE-3-CARBOXALDEHYDE 5-Ethoxy-3-indolecarboxaldehyde 5-ETHOXY-3-INDOLECARBOXALDEHYDE 5-ETHOXY-1H-INDOLE-3-CARBALDEHYDE 5-ethoxy-1H-indole-3-carboxaldehyde 1H-Indole-3-carboxaldehyde, 5-ethoxy-
CAS	169789-47-3
InChI	InChI=1/C11H11NO2/c1-2-14-9-3-4-11-10(5-9)8(7-13)6-12-11/h3-7,12H,2H2,1H3

1H-Indole-3-carboxaldehyde, 5-ethoxy- - Physico-chemical Properties

Molecular Formula	C11H11NO2
Molar Mass	189.21
Density	1.228±0.06 g/cm3(Predicted)
Boling Point	381.8±22.0 °C(Predicted)
Flash Point	184.7°C
Vapor Presure	4.94E-06mmHg at 25°C
pKa	15.26±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.655

1H-Indole-3-carboxaldehyde, 5-ethoxy- - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

1H-Indole-3-carboxaldehyde, 5-ethoxy- - Introduction

It is an organic compound with the chemical formula C13H11NO2.

Properties: It is a solid with a white or light yellow color. Its melting point is about 148-150 degrees Celsius, good thermal stability. It can be dissolved in many organic solvents, such as ethanol, dimethylformamide, etc., but it is insoluble in water.

Uses: It has important application value in the field of organic synthesis. It can be used as raw materials and intermediates in organic synthesis for the synthesis of various compounds with biological activity, such as drugs and pesticides. In addition, it can also be used in the field of light-emitting layer materials and optoelectronic devices of organic light-emitting diodes (OLEDs).

Preparation method: The preparation of the compound can be completed by the hydrogenation reaction of indole and the etherification reaction of ethanol. First, indole is hydrogenated with hydrogen in the presence of a suitable catalyst to give 5-indolomethanol. The 5-indolemethanol is then reacted with ethanol in the presence of a base to produce a bazol.

Safety information: Relevant safety information is relatively limited. As a chemical, use should be careful to comply with safe operating procedures and wear appropriate protective equipment. It may cause irritation to the eyes, skin and respiratory tract, so direct contact should be avoided. In the use and storage process should pay attention to fire and explosion prevention measures. Care should be taken to avoid its reaction with oxidants and strong acids. For more specific safety information, it is recommended to refer to the safety data sheet of the relevant chemical.

Last Update：2024-04-09 21:01:54